George Mason, Clearant Inc. Collaborate

Posted: June 22, 2001 at 1:00 am, Last Updated: November 30, -0001 at 12:00 am

By Patty Snellings

The School of Computational Sciences (SCS) and Clearant Inc., a molecular biosciences company based in Rockville, are pursuing a collaborative research program at the Prince William Campus to develop methods to characterize, purify, and sterilize proteins and cellular products from blood, plasma, and recombinant expression systems.

“Clearant Inc. is developing new methods for sterilization that remove inactive pathogens in blood products and recombinant proteins without losing the bioactive components of the proteins,” says Keith McKenney, SCS faculty member and principal George Mason researcher on the project. “The challenge of this research is that each protein is unique, which means one has to develop a technology that can be adapted to each specific protein. Our role is to contribute to the fundamental research that elucidates the principal products and reaction pathways in the process.”

Results will be of vital importance to the biopharmaceutical industry because every recombinant protein or blood product must be sterilized or purified away from contaminating viruses and microbes, he explains.

Clearant brings highly specialized instrumentation to the university’s labs, affording SCS graduate students the opportunity to use advanced technology equipment in their classes. In addition, Clearant scientists are internationally recognized for their research and expertise in molecular biosciences and have an excellent record in graduate teaching both in the classroom and the laboratory.

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